Govern high-risk research without turning scientific uncertainty into prohibited knowledge or allowing “research” to bypass personhood, consent, safety, evidence and constitutional limits.
Core structure
1. Research freedom is protected but not absolute.
2. Distinguish observation, simulation, intervention and deployment.
3. Research involving persons requires valid consent, independent review and risk minimization.
4. Simulated entities that meet legal-person criteria are not disposable experimental objects.
5. Dangerous capability research requires graded containment, access control and incident plans.
6. Dual-use findings may require staged disclosure rather than automatic secrecy or automatic publication.
7. Negative results and failed experiments remain protected institutional knowledge where material to safety.